Stem cells and burns: review and therapeutic implications.
J Burn Care Res
; 31(6): 874-81, 2010.
Article
em En
| MEDLINE
| ID: mdl-20859216
ABSTRACT
Despite significant advances in burn resuscitation and wound care over the past 30 years, morbidity and mortality from thermal injury remain high. Limited donor skin in severely burned patients hinders effective wound excision and closure, leading to infectious complications and prolonged hospitalizations. Even with large-volume fluid resuscitation, the systemic inflammatory response syndrome compromises end-organ perfusion in burn patients, with resultant multiorgan failure. Stem cells, which enhance wound healing and counteract systemic inflammation, now offer potential therapies for these challenges. Through a review of the literature, this article seeks to illustrate applications of stem cell therapy to burn care and to highlight promising areas of research.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Queimaduras
/
Síndrome de Resposta Inflamatória Sistêmica
/
Transplante de Células-Tronco
Limite:
Humans
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article