Vincristine-ticlopidine-aspirin: an effective therapy in children with Kasabach-Merritt phenomenon associated with vascular tumors.
Pediatr Hematol Oncol
; 27(8): 641-5, 2010 Nov.
Article
em En
| MEDLINE
| ID: mdl-20863161
ABSTRACT
Kasabach-Merritt phenomenon (KMP) is a serious coagulopathy with severe thrombocytopenia (<10,000/mm³) that occurs in the presence of an enlarging vascular tumor such as kaposiform hemangioendothelioma (KHE) and tufted angioma (TA). The natural history and treatment of these lesions remain controversial. The authors report a KHE case and a TA case that presented with KMP, describing their successful pharmacological management with vincristine, ticlopidine, and aspirin.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Vincristina
/
Ticlopidina
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Protocolos de Quimioterapia Combinada Antineoplásica
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Aspirina
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Neoplasias Vasculares
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Infant
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article