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[Unfractionated heparin and low molecular weight heparin for acute coronary syndromes--assessment of a Cochrane review]. / Ufraktioneret og lavmolekylaert heparin ved akutte koronare syndromer--en gennemgang af et Cochrane-review.
Husted, Steen Elkjaer; Nielsen, Hans Kraemmer.
Afiliação
  • Husted SE; Medicinsk-kardiologisk Afdeling, Århus Sygehus, Århus Universitetshospital, 8000 Århus C, Denmark. steehust@rm.dk
Ugeskr Laeger ; 172(42): 2888-91, 2010 Oct 18.
Article em Da | MEDLINE | ID: mdl-21040659
In aspirin-treated patients with acute coronary syndromes without ST-segment elevation unfractionated heparin (UFH) or low molecular weight heparin (LMWH) treatment < 7 days significantly reduce the risk of acute myocardial infarction (AMI), and LMWH furthermore reduces revascularisation. There is a non-significant effect on mortality compared with placebo and an insignificantly increased risk of haemorrhagic complications. No net clinical benefit of LMWH was found compared to UHF, but LMWH has pharmacokinetic advantages. The optimal duration of heparin treatment remains controversial.
Assuntos
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Base de dados: MEDLINE Assunto principal: Heparina / Heparina de Baixo Peso Molecular / Síndrome Coronariana Aguda / Fibrinolíticos / Anticoagulantes Tipo de estudo: Clinical_trials / Guideline Limite: Humans Idioma: Da Ano de publicação: 2010 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Heparina / Heparina de Baixo Peso Molecular / Síndrome Coronariana Aguda / Fibrinolíticos / Anticoagulantes Tipo de estudo: Clinical_trials / Guideline Limite: Humans Idioma: Da Ano de publicação: 2010 Tipo de documento: Article