Cat-Map: putting cataract on the map.
Mol Vis
; 16: 2007-15, 2010 Oct 08.
Article
em En
| MEDLINE
| ID: mdl-21042563
ABSTRACT
Lens opacities, or cataract(s), may be inherited as a classic Mendelian disorder usually with early-onset or, more commonly, acquired with age as a multi-factorial or complex trait. Many genetic forms of cataract have been described in mice and other animal models. Considerable progress has been made in mapping and identifying the genes and mutations responsible for inherited forms of cataract, and genetic determinants of age-related cataract are beginning to be discovered. To provide a convenient and accurate summary of current information focused on the increasing genetic complexity of Mendelian and age-related cataract we have created an online chromosome map and reference database for cataract in humans and mice (Cat-Map).
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Catarata
/
Mapeamento Cromossômico
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article