Water-soluble peptide-coated nanoparticles: control of the helix structure and enhanced differential binding to immune cells.
J Am Chem Soc
; 133(1): 8-11, 2011 Jan 12.
Article
em En
| MEDLINE
| ID: mdl-21142034
ABSTRACT
The stabilizing action of C(α)-tetrasubstituted α-amino acids inserted into a sequence of short peptides allowed for the first time the preparation of water-soluble nanoparticles of different materials coated with a helix-structured undecapeptide. This peptide coating strongly favors nanoparticle uptake by human immune system cells.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Peptídeos
/
Água
/
Nanopartículas
/
Sistema Imunitário
Limite:
Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article