Antiviral activity of Anaferon (pediatric formulation) in mice infected with pandemic influenza virus A(H1N1/09).
Bull Exp Biol Med
; 149(5): 612-4, 2010 Oct.
Article
em En
| MEDLINE
| ID: mdl-21165400
ABSTRACT
Anaferon (pediatric formulation) administered in the therapeutic-and-prophylactic regimen to mice receiving intranasally 100% infecting dose of A/California/07/2009(H1N1)v influenza virus exhibited an antiviral effect and 10-fold reduced the production of influenza virus in the lungs of infected mice on days 4, 6, and 8 after infection compared to the control (distilled water). The efficiency of Anaferon (pediatric formulation) administered before and after infection with A/California/07/2009(H1N1)v influenza virus was not inferior to the use of Tamiflu after infection.
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Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Infecções por Orthomyxoviridae
/
Anticorpos
Limite:
Animals
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article