Chemical priming for spinal cord injury: a review of the literature part II-potential therapeutics.
Childs Nerv Syst
; 27(8): 1307-16, 2011 Aug.
Article
em En
| MEDLINE
| ID: mdl-21174102
ABSTRACT
INTRODUCTION:
Spinal cord injury is a complex cascade of reactions secondary to the initial mechanical trauma that puts into action the innate properties of the injured cells, the circulatory, inflammatory, and chemical status around them, into a non-permissive and destructive environment for neuronal function and regeneration. Priming means putting a cell, in a state of "arousal" towards better function. Priming can be mechanical as trauma is known to enhance activity in cells. MATERIALS ANDMETHODS:
A comprehensive review of the literature was performed to better understand the possible chemical primers used for spinal cord injuries.CONCLUSIONS:
Taken together, many studies have shown various promising results using the substances outlined herein for treating SCI.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Traumatismos da Medula Espinal
/
Fatores de Crescimento Neural
/
Regeneração Nervosa
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article