Urticarial vasculitis associated with a monoclonal IgM gammopathy: Schnitzler's syndrome.
Br J Dermatol
; 123(1): 113-8, 1990 Jul.
Article
em En
| MEDLINE
| ID: mdl-2117969
ABSTRACT
We describe two cases of Schnitzler's syndrome presenting with urticarial vasculitis, in which there was a monoclonal IgM of kappa light-chain isotype. Skin histology showed a perivascular leucocytic infiltrate and leucocytoclasis. One patient had an abnormal complement profile and positive rheumatoid factor while the other had antibodies to unidentified soluble nuclear antigens, anti-cytoplasmic antibodies and circulating immune complexes. In addition, in the first case deposits of IgM, C3 and, to a lesser degree, of IgG were observed in the walls of small blood vessels.
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Base de dados:
MEDLINE
Assunto principal:
Paraproteinemias
/
Urticária
/
Vasculite
/
Imunoglobulina M
Tipo de estudo:
Risk_factors_studies
Limite:
Aged
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1990
Tipo de documento:
Article