[Evaluation of pulmonary microvascular permeability in isolated perfused rabbit lungs].

ABSTRACT

AIM: To quantity and accurately evaluate pulmonary microvascular permeability. METHODS: To measure capillary fluid filtration coefficient (Kf) by using the gravimetric method in isolated perfused rabbit lungs. RESULTS: The amount of Kf is 4.78 +/- 0.73 mg x min(-1) x cmH2O(-1) x g(-1). CONCLUSION: The advantage of this method is exactly and directly. This method shows the important effect on realizing the pulmonary physiologic condition and evaluating the extent of acute lung edema and injury.