Anticoagulation therapy: indications, monitoring, and complications.
Pediatr Emerg Care
; 27(1): 55-61; quiz 62-4, 2011 Jan.
Article
em En
| MEDLINE
| ID: mdl-21206260
ABSTRACT
Anticoagulation for thromboembolic disease and bleeding, the main complication of anticoagulation therapy, are uncommon but are potentially life- or limb-threatening conditions that may present in the pediatric emergency department. Thromboembolic disease in children usually occurs as a complication of vascular access, primarily in children with congenital heart disease or cancer. However, complications of anticoagulation therapy used in the treatment of venous thromboembolism, pulmonary embolism, and blocked central venous catheter; arterial thromboembolism, including arterial ischemic stroke, Kawasaki disease, and after cardiac surgery, may warrant a visit to n the pediatric emergency department. Anticoagulation therapy may take the form of unfractionated heparin, low-molecular weight heparin, vitamin K antagonists, acetylsalicylic acid, or thrombolytic therapy. Monitoring anticoagulation therapy in children is very important and follows adult guidelines. Anticoagulant dosing may be adjusted based on activated partial thromboplastin time, anti-factor Xa level, and international normalized ratio.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tromboembolia
/
Coagulação Sanguínea
/
Anticoagulantes
Tipo de estudo:
Guideline
Limite:
Child
/
Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article