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Antitumor quinol PMX464 is a cytocidal anti-trypanosomal inhibitor targeting trypanothione metabolism.
König, Janine; Wyllie, Susan; Wells, Geoffrey; Stevens, Malcolm F; Wyatt, Paul G; Fairlamb, Alan H.
Afiliação
  • König J; From the Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH and.
  • Wyllie S; From the Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH and.
  • Wells G; the Centre for Biomolecular Sciences, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
  • Stevens MF; the Centre for Biomolecular Sciences, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
  • Wyatt PG; From the Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH and.
  • Fairlamb AH; From the Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH and. Electronic address: a.h.fairlamb@dundee.ac.uk.
J Biol Chem ; 286(10): 8523-8533, 2011 Mar 11.
Article em En | MEDLINE | ID: mdl-21212280

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tripanossomicidas / Trypanosoma brucei brucei / Benzotiazóis / Hidroquinonas / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2011 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tripanossomicidas / Trypanosoma brucei brucei / Benzotiazóis / Hidroquinonas / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2011 Tipo de documento: Article