The Drosophila melanogaster z600 gene encodes a chromatin-associated protein synthesized in the syncytial blastoderm.
Gene
; 96(2): 227-32, 1990 Dec 15.
Article
em En
| MEDLINE
| ID: mdl-2125289
ABSTRACT
The Drosophila melanogaster z600 gene is zygotically expressed with gene transcripts accumulating transiently during early embryogenesis. Based on nucleotide sequence analysis, z600 is predicted to encode a small, basic, histone-like protein. Antibodies generated against a beta-galactosidasez600 fusion protein immunoprecipitated the z600 in vitro translation product and detected a z600 protein present predominantly in 2- to 4-h embryos. We localized the z600 protein in whole-amount embryos by indirect immunofluorescence. These studies show that the protein is located in the nucleus and associated with chromatin in the syncytial blastoderm.
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Base de dados:
MEDLINE
Assunto principal:
Blastoderma
/
Proteínas Nucleares
/
Cromatina
/
Drosophila melanogaster
Tipo de estudo:
Risk_factors_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
1990
Tipo de documento:
Article