[Serological evaluation of immunization against measles with 2 doses administered at 6 and 11 months of age: a prospective study]. / Avaliação sorológica de imunização contra o sarampo com duas doses administradas aos 6 e 11 meses de idade: estudo prospectivo.
Rev Inst Med Trop Sao Paulo
; 32(6): 450-5, 1990.
Article
em Pt
| MEDLINE
| ID: mdl-2135492
ABSTRACT
A prospective study was designed to evaluate the serologic efficacy of a two dose measles vaccination schedule, at 6 months and 11 months of age. Infants were given a further attenuated measles virus vaccine (BIKEN CAM 70, Fundação Oswaldo Cruz) and serum samples were tested for measles antibodies using the indirect immunofluorescence technique (IFA) and ELISA. Seroconversion rates 6 to 12 months (mean of 8.0 +/- 1.7 months) following the second dose of measles vaccine were 88.5% (85/96) by IFA and 96.8% (93/96) by ELISA. No measles cases were reported during the study period. In regions where a significant proportion of measles cases occurs before nine months of age, vaccination with a two doses schedule, at 6 and 11 months of age, may represent an alternative for measles control.
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Base de dados:
MEDLINE
Assunto principal:
Vacina contra Sarampo
/
Esquemas de Imunização
/
Imunização Secundária
/
Sarampo
Tipo de estudo:
Observational_studies
Limite:
Humans
/
Infant
Idioma:
Pt
Ano de publicação:
1990
Tipo de documento:
Article