Crystallization of the Staphylococcus aureus MazF mRNA interferase.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 67(Pt 3): 386-9, 2011 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-21393849
ABSTRACT
mazEF modules encode toxin-antitoxin pairs that are involved in the bacterial stress response through controlled and specific degradation of mRNA. Staphylococcus aureus MazF and MazE constitute a unique toxin-antitoxin module under regulation of the sigB operon. A MazF-type mRNA interferase is combined with an antitoxin of unknown fold. Crystals of S. aureus MazF (SaMazF) were grown in space group P2(1)2(1)2(1). The crystals diffracted to 2.1â
Å resolution and are likely to contain two SaMazF dimers in the asymmetric unit.
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Base de dados:
MEDLINE
Assunto principal:
Staphylococcus aureus
/
Proteínas de Bactérias
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RNA Mensageiro
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Proteínas de Ligação a DNA
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Endorribonucleases
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article