Secondary pulmonary alveolar proteinosis after unrelated cord blood hematopoietic cell transplantation.
Pediatr Transplant
; 16(5): E146-9, 2012 Aug.
Article
em En
| MEDLINE
| ID: mdl-21395954
ABSTRACT
PAP is a rare alveolointerstitial lung disorder characterized histologically by the intra-alveolar accumulation of eosinophilic and PAS-positive material. We observed two cases of PAP after unrelated CB hematopoietic progenitor cell transplantation in children with ALL. No antagonist activity toward GM-CSF was identified in the patient tested. The putative multifactorial PAP etiology is discussed. This potentially curable condition should be considered in a CB allograft recipient with alveolointerstial lung disorder.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Complicações Pós-Operatórias
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Proteinose Alveolar Pulmonar
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Transplante de Células-Tronco Hematopoéticas
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Transplante de Células-Tronco de Sangue do Cordão Umbilical
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Leucemia-Linfoma Linfoblástico de Células Precursoras
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Adolescent
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Child, preschool
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article