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Influence of donor cytomegalovirus (CMV) status on severity of viral reactivation after allogeneic stem cell transplantation in CMV-seropositive recipients.
Pietersma, Floor L; van Dorp, Suzanne; Minnema, Monique C; Kuball, Jürgen; Meijer, Ellen; Schuurman, Rob; van Baarle, Debbie.
Afiliação
  • Pietersma FL; Deparment of Immunology, Erasmus Medical Center, Rotterdam, The Netherlands.
Clin Infect Dis ; 52(7): e144-8, 2011 Apr 01.
Article em En | MEDLINE | ID: mdl-21427386
We investigated the role of donor cytomegalovirus (CMV) serostatus on reactivation of CMV infection in CMV-infected transplant recipients. Reactivation of CMV infection occurred more frequently in patients receiving a CMV-positive graft but was less severe than in patients receiving a CMV-negative graft. These data suggest roles for both virus as well as CMV-specific immunity present in the graft.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doadores de Tecidos / Ativação Viral / Índice de Gravidade de Doença / Infecções por Citomegalovirus / Citomegalovirus / Transplante de Células-Tronco Tipo de estudo: Incidence_studies / Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2011 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doadores de Tecidos / Ativação Viral / Índice de Gravidade de Doença / Infecções por Citomegalovirus / Citomegalovirus / Transplante de Células-Tronco Tipo de estudo: Incidence_studies / Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2011 Tipo de documento: Article