[Level of evidence for therapeutic drug monitoring of teicoplatin]. / Niveau de preuve du suivi thérapeutique pharmacologique de la teicoplanine.
Therapie
; 66(1): 45-50, 2011.
Article
em Fr
| MEDLINE
| ID: mdl-21466777
ABSTRACT
Teicoplanin is a glycopeptid antibiotic used for treatment of serious infections caused by Gram+ bacteriae. The treatment scheme corresponds to an initial loading dose followed by maintenance dose. High interindividual pharmacokinetic variability and strong relation between high through concentrations, dose and clinical success, support the need of therapeutic drug monitoring using through concentrations. Achieving through concentrations ≥ 10-15 mg/L or ≥ 20-40 mg/L, regarding the measurement method and the infection severity, is recommended to increase clinical success rate. The level of proof of therapeutic drug monitoring is evaluated "necessary".
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Base de dados:
MEDLINE
Assunto principal:
Infecções Bacterianas
/
Monitoramento de Medicamentos
/
Teicoplanina
/
Antibacterianos
Limite:
Humans
Idioma:
Fr
Ano de publicação:
2011
Tipo de documento:
Article