Evidence-based guideline: treatment of painful diabetic neuropathy--report of the American Association of Neuromuscular and Electrodiagnostic Medicine, the American Academy of Neurology, and the American Academy of Physical Medicine & Rehabilitation.
Muscle Nerve
; 43(6): 910-7, 2011 Jun.
Article
em En
| MEDLINE
| ID: mdl-21484835
ABSTRACT
The objective of this report was to develop a scientifically sound and clinically relevant evidence-based guideline for the treatment of painful diabetic neuropathy (PDN). The basic question that was asked was "What is the efficacy of a given treatment (pharmacological anticonvulsants, antidepressants, opioids, others; non-pharmacological electrical stimulation, magnetic field treatment, low-intensity laser treatment, Reiki massage, others) to reduce pain and improve physical function and quality of life (QOL) in patients with PDN?" A systematic review of literature from 1960 to August 2008 was performed, and studies were classified according to the American Academy of Neurology classification of evidence scheme for a therapeutic article. Recommendations were linked to the strength of the evidence. The results indicate that pregabalin is established as effective and should be offered for relief of PDN (Level A). Venlafaxine, duloxetine, amitriptyline, gabapentin, valproate, opioids (morphine sulfate, tramadol, and oxycodone controlled-release), and capsaicin are probably effective and should be considered for treatment of PDN (Level B). Other treatments have less robust evidence, or the evidence is negative. Effective treatments for PDN are available, but many have side effects that limit their usefulness. Few studies have sufficient information on their effects on function and QOL.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Terapia Combinada
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Medicina Baseada em Evidências
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Neuropatias Diabéticas
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Doenças do Sistema Nervoso
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Doenças Neuromusculares
Tipo de estudo:
Guideline
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Risk_factors_studies
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Systematic_reviews
Limite:
Humans
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article