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Iridoids from leaves of Gelsemium elegans.
Zhang, Bin-Feng; Zhang, Qiu-Ping; Liu, Hai; Chou, Gui-Xin; Wang, Zheng-Tao.
Afiliação
  • Zhang BF; The MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Cai Lun Road 1200, Zhangjiang, Shanghai 201210, China; Shanghai R&D Center for Standardization of Chinese Medicines, Shanghai 201210, China.
  • Zhang QP; The MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Cai Lun Road 1200, Zhangjiang, Shanghai 201210, China; Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China.
  • Liu H; The MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Cai Lun Road 1200, Zhangjiang, Shanghai 201210, China; Shanghai R&D Center for Standardization of Chinese Medicines, Shanghai 201210, China.
  • Chou GX; The MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Cai Lun Road 1200, Zhangjiang, Shanghai 201210, China; Shanghai R&D Center for Standardization of Chinese Medicines, Shanghai 201210, China.
  • Wang ZT; The MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Cai Lun Road 1200, Zhangjiang, Shanghai 201210, China; Shanghai R&D Center for Standardization of Chinese Medicines, Shanghai 201210, China.
Phytochemistry ; 72(9): 916-22, 2011 Jun.
Article em En | MEDLINE | ID: mdl-21497867
ABSTRACT
Six iridoids, geleganoids, designated A-F, and five iridoid glycosides, geleganosides A and B together with three previously reported compounds, were isolated from leaves of Gelsemium elegans. Their structures were elucidated by spectroscopic and chemical analyses. The relative configuration of geleganoid A was confirmed by X-ray crystallographic diffraction analysis, and the absolute configuration of geleganoid B was determined by a modified Mosher's method. Selected compounds were evaluated for PC12 cell neurite outgrowth activity, but they were inactive.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gelsemium / Glicosídeos Iridoides Limite: Animals Idioma: En Ano de publicação: 2011 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gelsemium / Glicosídeos Iridoides Limite: Animals Idioma: En Ano de publicação: 2011 Tipo de documento: Article