Quantum dot-aptamer nanoprobes for recognizing and labeling influenza A virus particles.
Nanoscale
; 3(6): 2454-7, 2011 Jun.
Article
em En
| MEDLINE
| ID: mdl-21509395
ABSTRACT
The fluorescence labeling of viruses is a useful technology for virus detection and imaging. By combining the excellent fluorescence properties of quantum dots (QDs) with the high affinity and specificity of aptamers, we constructed a QD-aptamer probe. The aptamer A22, against the hemagglutinin of influenza A virus, was linked to QDs, producing the QD-A22 probe. Fluorescence imaging and transmission electron microscopy showed that the QD-A22 probe could specifically recognize and label influenza A virus particles. This QD labeling technique provides a new strategy for labeling virus particles for virus detection and imaging.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Vírus da Influenza A
/
Pontos Quânticos
/
Aptâmeros de Nucleotídeos
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article