Part 1: N-alkylated glycines as potent α2δ ligands.
Bioorg Med Chem Lett
; 21(12): 3764-6, 2011 Jun 15.
Article
em En
| MEDLINE
| ID: mdl-21601457
ABSTRACT
A new series of glycine-derived ligands of the α(2)δ subunit of voltage gated calcium channels is described. Several novel compounds (7) based on (6) were prepared that possessed a potency <100 nM in the α(2)δ binding assay.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Canais de Cálcio
/
Glicina
/
Ligantes
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article