Association of polymorphisms in HTR2A, HTR1A and TPH2 genes with suicide attempts in alcohol dependence: a preliminary report.
Psychiatry Res
; 190(1): 149-51, 2011 Nov 30.
Article
em En
| MEDLINE
| ID: mdl-21621273
ABSTRACT
We investigated a relationship between selected polymorphisms rs6313 in HTR2A, rs6295 in HTR1A and rs1386494 in TPH2, and suicidal behaviour in 150 alcohol-dependent patients. There was a significant association between more frequent C102C genotype in HTR2A and suicide attempts in alcoholic females. No differences in genotype distribution in HTR1A and TPH2 SNPs were found between patients with and without suicide attempts.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tentativa de Suicídio
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Triptofano Hidroxilase
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Predisposição Genética para Doença
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Polimorfismo de Nucleotídeo Único
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Receptor 5-HT1A de Serotonina
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Receptor 5-HT2A de Serotonina
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Alcoolismo
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article