Synaptic vesicle retrieval time is a cell-wide rather than individual-synapse property.
Nat Neurosci
; 14(7): 824-6, 2011 May 29.
Article
em En
| MEDLINE
| ID: mdl-21623361
ABSTRACT
Although individual nerve terminals from the same neuron often differ in neurotransmitter release characteristics, the extent to which endocytic retrieval of synaptic vesicle components differs is unknown. We used high-fidelity optical recordings to undertake a large-scale analysis of endocytosis kinetics of individual boutons in hippocampal rat neurons. Our data indicate that endocytosis kinetics do not differ substantially across boutons from the same cell but instead appear to be controlled at a cell-wide level.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sinapses
/
Vesículas Sinápticas
/
Terminações Pré-Sinápticas
/
Neurônios
Tipo de estudo:
Health_economic_evaluation
/
Prognostic_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article