Wall teichoic Acid-dependent adsorption of staphylococcal siphovirus and myovirus.

Xia, Guoqing; Corrigan, Rebecca M; Winstel, Volker; Goerke, Christiane; Gründling, Angelika; Peschel, Andreas

Xia, Guoqing; Corrigan, Rebecca M; Winstel, Volker; Goerke, Christiane; Gründling, Angelika; Peschel, Andreas.

Afiliação

Xia G; Cellular and Molecular Microbiology Section, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Elfriede-Aulhorn-Strasse 6, D-72076 Tübingen, Germany. guoqing.xia@med.uni-tuebingen.de

J Bacteriol ; 193(15): 4006-9, 2011 Aug.

Article em En | MEDLINE | ID: mdl-21642458

ABSTRACT

ABSTRACT

The molecular interactions between staphylococcal phages and host cell surfaces are poorly understood. Employing Staphylococcus aureus teichoic acid mutants, we demonstrate that wall teichoic acid (WTA), but not lipoteichoic acid, serves as a receptor for staphylococcal siphovirus and myovirus, while only the siphovirus requires glycosylated WTA.

Assuntos

Receptores Virais/metabolismo; Fagos de Staphylococcus/fisiologia; Staphylococcus aureus/metabolismo; Staphylococcus aureus/virologia; Ácidos Teicoicos/metabolismo; Parede Celular/metabolismo; Parede Celular/virologia; Glicosilação; Mutação; Staphylococcus aureus/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Virais / Staphylococcus aureus / Ácidos Teicoicos / Fagos de Staphylococcus Idioma: En Ano de publicação: 2011 Tipo de documento: Article

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