Lack of association between genetic variations in the KALRN region and ischemic stroke.
Clin Biochem
; 44(12): 1018-20, 2011 Aug.
Article
em En
| MEDLINE
| ID: mdl-21664346
OBJECTIVES: To investigate whether KALRN gene variation is associated with ischemic stroke (IS). DESIGN AND METHODS: Associations to overall IS and IS subtypes were investigated in SAHLSIS, which comprises 844 patients with IS and 668 controls. RESULTS: Associations between KALRN SNPs and overall IS and cardioembolic stroke were detected. Associations for overall IS were investigated in two additional Swedish samples, but could not be replicated. CONCLUSION: KALRN gene variation is not associated with overall IS.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Isquemia Encefálica
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Proteínas Serina-Treonina Quinases
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Acidente Vascular Cerebral
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Fatores de Troca do Nucleotídeo Guanina
/
Polimorfismo de Nucleotídeo Único
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article