BioGraph: unsupervised biomedical knowledge discovery via automated hypothesis generation.
Genome Biol
; 12(6): R57, 2011 Jun 22.
Article
em En
| MEDLINE
| ID: mdl-21696594
ABSTRACT
We present BioGraph, a data integration and data mining platform for the exploration and discovery of biomedical information. The platform offers prioritizations of putative disease genes, supported by functional hypotheses. We show that BioGraph can retrospectively confirm recently discovered disease genes and identify potential susceptibility genes, outperforming existing technologies, without requiring prior domain knowledge. Additionally, BioGraph allows for generic biomedical applications beyond gene discovery. BioGraph is accessible at http//www.biograph.be.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Software
/
Biologia Computacional
/
Mineração de Dados
Limite:
Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article