Long-term time course of affective lability after subthalamic deep brain stimulation electrode implantation.
Neurocase
; 17(6): 527-32, 2011 Dec.
Article
em En
| MEDLINE
| ID: mdl-21707232
ABSTRACT
The mechanism and time course of emotional side effects of subthalamic deep brain stimulation in Parkinson's disease are a matter for discussion. We report a 53-month follow-up of a patient with affective lability. Postoperative lesion plus bilateral stimulation strongly influenced mood in the first week in terms of laughing behavior, while voltage changes had only minor long-term impact up to 37 months on negative emotion, possibly caused by the right electrode stimulating the subthalamic nucleus and adjacent fiber tracts involving the internal capsule. Thus we conclude that affective lability can occur with different temporal dynamics of microlesion, and early and chronic stimulation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
/
Sintomas Afetivos
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Estimulação Encefálica Profunda
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article