CDC/NIH Workshop. Tuberculosis biomarker and surrogate endpoint research roadmap.
Am J Respir Crit Care Med
; 184(8): 972-9, 2011 Oct 15.
Article
em En
| MEDLINE
| ID: mdl-21737585
ABSTRACT
The Centers for Disease Control and Prevention and National Institutes of Health convened a multidisciplinary meeting to discuss surrogate markers of treatment response in tuberculosis. The goals were to assess recent surrogate marker research and to provide specific recommendations for (1) the qualification and validation of biomarkers of treatment outcome; (2) the standardization of specimen and data collection for future clinical trials, including a minimum set of samples and collection time points; and (3) the creation ofa specimen repository to support biomarker testing. This article summarizes these recommendations and provides a roadmap for their implementation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Manejo de Espécimes
/
Tuberculose
/
Biomarcadores
/
Ensaios Clínicos como Assunto
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article