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Lyme disease-associated glomerulonephritis.
Mc Causland, Finnian R; Niedermaier, Sophie; Bijol, Vanesa; Rennke, Helmut G; Choi, Mary E; Forman, John P.
Afiliação
  • Mc Causland FR; Renal Division, Brigham and Women's Hospital, Boston, MA, USA. fmccausland@partners.org
Nephrol Dial Transplant ; 26(9): 3054-6, 2011 Sep.
Article em En | MEDLINE | ID: mdl-21750163
We report two cases of Lyme disease-associated glomerulonephritis. A 57-year-old female presented with rash, volume overload, hypertension and rapidly progressive glomerulonephritis. Biopsy confirmed an immune complex-mediated, membranoproliferative lesion. She was treated successfully with steroids and antibiotics. In a second case, a 40-year-old male, with a previously known microscopic hematuria, presented with rash, arthralgias, new proteinuria and gross hematuria following a tick bite. Biopsy revealed focal proliferative IgA nephropathy. Treatment with steroids and antibiotics resulted in rapid resolution of findings. Acute Lyme disease may contribute to the development of de novo, or activation of previously quiescent, immune-mediated glomerular disease.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Lyme / Glomerulonefrite Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2011 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Lyme / Glomerulonefrite Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2011 Tipo de documento: Article