Characterization of in vivo metabolites of WR319691, a novel compound with activity against Plasmodium falciparum.

Milner, Erin; Sousa, Jason; Pybus, Brandon; Melendez, Victor; Gardner, Sean; Grauer, Kristina; Moon, Jay; Carroll, Dustin; Auschwitz, Jennifer; Gettayacamin, Montip; Lee, Patricia; Leed, Susan; McCalmont, William; Norval, Suzanne; Tungtaeng, Anchalee; Zeng, Qiang; Kozar, Michael; Read, Kevin D; Li, Qigui; Dow, Geoffrey

Milner, Erin; Sousa, Jason; Pybus, Brandon; Melendez, Victor; Gardner, Sean; Grauer, Kristina; Moon, Jay; Carroll, Dustin; Auschwitz, Jennifer; Gettayacamin, Montip; Lee, Patricia; Leed, Susan; McCalmont, William; Norval, Suzanne; Tungtaeng, Anchalee; Zeng, Qiang; Kozar, Michael; Read, Kevin D; Li, Qigui; Dow, Geoffrey.

Afiliação

Milner E; Department of Medicinal Chemistry, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD 20910-7500, USA, erin.milner@amedd.army.mil

Eur J Drug Metab Pharmacokinet ; 36(3): 151-8, 2011 Sep.

Article em En | MEDLINE | ID: mdl-21751074

Assuntos

Antimaláricos/metabolismo; Plasmodium falciparum/efeitos dos fármacos; Quinolinas/metabolismo; Animais; Encéfalo/metabolismo; Fígado/metabolismo; Masculino; Camundongos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Quinolinas / Antimaláricos Limite: Animals Idioma: En Ano de publicação: 2011 Tipo de documento: Article

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