A synopsis of current care of thalassaemia major patients in Hong Kong.
Hong Kong Med J
; 17(4): 261-6, 2011 Aug.
Article
em En
| MEDLINE
| ID: mdl-21813892
ABSTRACT
OBJECTIVE:
To provide a synopsis of current thalassaemia major patient care in Hong Kong.DESIGN:
Retrospective study.SETTING:
All haematology units of the Hospital Authority in Hong Kong. PATIENTS All patients with thalassaemia major with regular transfusion.RESULTS:
To date, there were 363 thalassaemia major patients under the care of the Hospital Authority. Prenatal diagnosis has helped to reduce the number of indigenous new cases, but in recent years immigrant cases are appearing. The patients have a mean age of 23 (range, 1-52) years, and 78% of them are adults. In 2009, they received 18 782 units of blood. This accounted for 9.5% of all blood consumption from the Hong Kong Red Cross. In the past, cardiac iron overload was the major cause of death (65%) and few patients survived beyond the age of 45 years. The availability of cardiac iron assessment by magnetic resonance imaging (T2 MRI) to direct the use of oral deferiprone chelation has reduced the prevalence of heart failure and cardiac haemosiderosis, which should reduce mortality and improve life expectancy.CONCLUSION:
The future for thalassaemia care in Hong Kong is bright. With better transfusion and chelation, it should be possible to avoid growth and endocrine deficiencies in younger patients.
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Base de dados:
MEDLINE
Assunto principal:
Talassemia
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Humans
/
Infant
/
Middle aged
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article