Supravital fluorometric apoptosis detection in a single mouse embryo using lab-on-a-chip.
Lab Chip
; 11(19): 3263-8, 2011 Oct 07.
Article
em En
| MEDLINE
| ID: mdl-21833426
ABSTRACT
Detection of apoptosis is one of the main criteria of preimplantation embryo growth potential assessment. Recent developments in lab-on-a-chip techniques has led to apoptosis detection and monitoring on a single cell or embryo level. However, single embryo apoptosis detection without a change in embryo developmental competence and post-examination "recovery" still remains a challenge. In this paper we present a lab-on-a-chip, co-working with miniaturized optical instrumentation, which allows supravital examination of single embryos for the presence of apoptotic blastomers with full after lab-on-a-chip study "recovery" and maintenance of their further developmental capacity.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Apoptose
/
Embrião de Mamíferos
/
Fluorometria
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article