CT angiographic measurement of vascular blood flow velocity by using projection data.
Radiology
; 261(3): 923-9, 2011 Dec.
Article
em En
| MEDLINE
| ID: mdl-21969665
ABSTRACT
PURPOSE:
To determine whether flow velocity can be measured by using projection data from computed tomographic (CT) scans obtained during contrast material injection in a phantom model. MATERIALS ANDMETHODS:
The authors constructed a 12.7-mm-diameter single-channel flow phantom with constant water flow velocity settings of 25.3, 43.9, and 70.5 cm/sec. For each flow velocity, serial axial scans were obtained with 16-section multidetector CT while a 10-mL bolus of contrast material was injected upstream of the imaging plane. For each bolus injection, the CT projection data from the scan with the sharpest increase in magnitude of detected contrast material was used for flow velocity measurements. Flow velocity was calculated as the ratio of distance between CT detector rows and the corresponding time lag in the contrast enhancement curves and was correlated with the reference velocities. Five separate contrast material injections and CT measurements were made for each flow velocity setting.RESULTS:
The correlation coefficient between the CT measurements of flow velocity and the reference measurements was 0.98 (P < .05). The mean CT measurements of flow velocity were 34.2, 53.9, and 80.8 cm/sec for slow, moderate, and fast velocity settings, respectively, overestimating the corresponding actual flow velocities by 26%, 18%, and 13% and showing precision values (coefficients of variation) of 5.2%, 3.7%, and 6.6%.CONCLUSION:
Flow velocity can be measured from row-to-row multidetector CT projectional data obtained during a single gantry revolution as a bolus of contrast material flows through a vascular phantom. With further development, this novel technique could potentially provide physiologic information to complement the anatomic CT angiographic findings of vascular disease.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Velocidade do Fluxo Sanguíneo
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Iohexol
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Angiografia
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Tomografia Computadorizada por Raios X
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Imagem Radiográfica a Partir de Emissão de Duplo Fóton
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Meios de Contraste
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article