Expression of vitellogenin in the testis and kidney of the spotted ray Torpedo marmorata exposed to 17ß-estradiol.
Gen Comp Endocrinol
; 174(3): 318-25, 2011 Dec 01.
Article
em En
| MEDLINE
| ID: mdl-21983423
ABSTRACT
In vertebrates, the liver was long thought to be the only site of vitellogenin (Vtg) production, but recent studies demonstrated that Vtg is also expressed in extrahepatic districts. The aim of this paper is to assess, by in situ hybridization and immunohistochemistry, the expression of Vtg in the testis and kidney of Torpedo marmorata exposed to 17ß-estradiol (E(2)). In treated samples vtg mRNA and Vtg were detected contemporaneously only in the testis; differently the kidney cells were positive to Vtg antibody, but negative to vtg mRNA. This is the first study to assess that male germ cells, after an exposure to E(2), synthesize Vtg in a stage-dependent manner. The presence of Vtg and the modifications observed in the kidney after E(2) treatment are discussed.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Testículo
/
Torpedo
/
Vitelogeninas
/
Regulação da Expressão Gênica
/
Estradiol
/
Rim
Limite:
Animals
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article