From systems biology to systems biomedicine.
Curr Opin Biotechnol
; 23(4): 604-8, 2012 Aug.
Article
em En
| MEDLINE
| ID: mdl-22119097
ABSTRACT
Systems Biology is about combining theory, technology, and targeted experiments in a way that drives not only data accumulation but knowledge as well. The challenge in Systems Biomedicine is to furthermore translate mechanistic insights in biological systems to clinical application, with the central aim of improving patients' quality of life. The challenge is to find theoretically well-chosen models for the contextually correct and intelligible representation of multi-scale biological systems. In this review, we discuss the current state of Systems Biology, highlight the emergence of Systems Biomedicine, and highlight some of the topics and views that we think are important for the efficient application of Systems Theory in Biomedicine.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Biologia de Sistemas
/
Modelos Biológicos
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article