Decomposition of warning effects in Parkinson's disease.
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn
; 19(3): 433-47, 2012.
Article
em En
| MEDLINE
| ID: mdl-22149180
ABSTRACT
Neutral warning signals speed voluntary reactions by reducing temporal uncertainty and by triggering a brief burst of arousal. We attempted to isolate the phasic arousal mechanism in people with Parkinson's disease (PD) using a clock display to minimize temporal uncertainty. In this condition, the speeding of responses in a color-discrimination task by an accessory stimulus was the fully equivalent to the effect in age-matched control subjects. This indicates preserved phasic arousal in PD. Temporal preparation based on warning cues also appeared to be normal. By contrast, in a condition with high temporal uncertainty, the accessory stimulus (an air puff to the foot) impaired accuracy for the patients but not the neurologically normal subjects. The data are consistent with the view that PD disrupts internal but not external control of alertness.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
/
Nível de Alerta
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Transtornos Cognitivos
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Sinais (Psicologia)
Tipo de estudo:
Etiology_studies
Limite:
Aged
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article