New functionalizable alkyltrichlorosilane surface modifiers for biosensor and biomedical applications.
Langmuir
; 28(5): 2318-22, 2012 Feb 07.
Article
em En
| MEDLINE
| ID: mdl-22268643
ABSTRACT
We report herein three unprecedented alkyltrichlorosilane surface modifiers bearing pentafluorophenyl ester (PFP), benzothiosulfonate (BTS), or novel ß-propiolactone (BPL) functionalizable terminal groups. Evidence is provided that these molecules can be prepared in very high purity (as assessed by NMR) through a last synthetic step of Pt-catalyzed alkene hydrosilylation then directly employed, without further purification, for the surface modification of quartz and medical grade stainless steel. Subsequent on-surface functionalizations with amine and thiol model molecules demonstrate the potential of these molecular adlayers to be important platforms for future applications in the bioanalytical and biomedical fields.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Silanos
/
Técnicas Biossensoriais
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Tecnologia Biomédica
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article