The Ph1 locus suppresses Cdk2-type activity during premeiosis and meiosis in wheat.
Plant Cell
; 24(1): 152-62, 2012 Jan.
Article
em En
| MEDLINE
| ID: mdl-22274628
ABSTRACT
Despite possessing multiple sets of related (homoeologous) chromosomes, hexaploid wheat (Triticum aestivum) restricts pairing to just true homologs at meiosis. Deletion of a single major locus, Pairing homoeologous1 (Ph1), allows pairing of homoeologs. How can the same chromosomes be processed as homologs instead of being treated as nonhomologs? Ph1 was recently defined to a cluster of defective cyclin-dependent kinase (Cdk)-like genes showing some similarity to mammalian Cdk2. We reasoned that the cluster might suppress Cdk2-type activity and therefore affect replication and histone H1 phosphorylation. Our study does indeed reveal such effects, suggesting that Cdk2-type phosphorylation has a major role in determining chromosome specificity during meiosis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Plantas
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Triticum
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Quinase 2 Dependente de Ciclina
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Meiose
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article