First in vivo use of a capacitive micromachined ultrasound transducer array-based imaging and ablation catheter.
J Ultrasound Med
; 31(2): 247-56, 2012 Feb.
Article
em En
| MEDLINE
| ID: mdl-22298868
ABSTRACT
OBJECTIVES:
The primary objective was to test in vivo for the first time the general operation of a new multifunctional intracardiac echocardiography (ICE) catheter constructed with a microlinear capacitive micromachined ultrasound transducer (ML-CMUT) imaging array. Secondarily, we examined the compatibility of this catheter with electroanatomic mapping (EAM) guidance and also as a radiofrequency ablation (RFA) catheter. Preliminary thermal strain imaging (TSI)-derived temperature data were obtained from within the endocardium simultaneously during RFA to show the feasibility of direct ablation guidance procedures.METHODS:
The new 9F forward-looking ICE catheter was constructed with 3 complementary technologies a CMUT imaging array with a custom electronic array buffer, catheter surface electrodes for EAM guidance, and a special ablation tip, that permits simultaneous TSI and RFA. In vivo imaging studies of 5 anesthetized porcine models with 5 CMUT catheters were performed.RESULTS:
The ML-CMUT ICE catheter provided high-resolution real-time wideband 2-dimensional (2D) images at greater than 8 MHz and is capable of both RFA and EAM guidance. Although the 24-element array aperture dimension is only 1.5 mm, the imaging depth of penetration is greater than 30 mm. The specially designed ultrasound-compatible metalized plastic tip allowed simultaneous imaging during ablation and direct acquisition of TSI data for tissue ablation temperatures. Postprocessing analysis showed a first-order correlation between TSI and temperature, permitting early development temperature-time relationships at specific myocardial ablation sites.CONCLUSIONS:
Multifunctional forward-looking ML-CMUT ICE catheters, with simultaneous intracardiac guidance, ultrasound imaging, and RFA, may offer a new means to improve interventional ablation procedures.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transdutores
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Ecocardiografia
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Cateterismo Cardíaco
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Ablação por Cateter
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Ultrassonografia de Intervenção
Limite:
Animals
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article