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What is the best choice of partner chemotherapy with trastuzumab for metastatic breast cancer?
Gourmelon, Carole; Frenel, Jean Sébastien; Campone, Mario.
Afiliação
  • Gourmelon C; Institut du Cancer de l'Ouest Centre René Gauducheau, Bd Jacques Monod, 44805 Saint-Herblain, France.
Expert Rev Anticancer Ther ; 12(2): 195-201, 2012 Feb.
Article em En | MEDLINE | ID: mdl-22316367
The HER2 gene and its role in pathogenicity in human breast cancer were detected in the 1980s. Trastuzumab is a monoclonal antibody directed against the HER2 membrane receptor. The aim of this article is to describe chemotherapy-trastuzumab combinations that have been evaluated in patients with HER2-positive metastatic breast cancer, and to define the possible standards and options.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Receptor ErbB-2 / Anticorpos Monoclonais Humanizados Tipo de estudo: Clinical_trials Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2012 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Receptor ErbB-2 / Anticorpos Monoclonais Humanizados Tipo de estudo: Clinical_trials Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2012 Tipo de documento: Article