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A selenium analogue of firefly D-luciferin with red-shifted bioluminescence emission.
Conley, Nicholas R; Dragulescu-Andrasi, Anca; Rao, Jianghong; Moerner, W E.
Afiliação
  • Conley NR; Department of Chemistry, Stanford University, CA 94305-5080, USA.
Angew Chem Int Ed Engl ; 51(14): 3350-3, 2012 Apr 02.
Article em En | MEDLINE | ID: mdl-22344705
A selenium analogue of amino-D-luciferin, aminoseleno-D-luciferin, is synthesized and shown to be a competent substrate for the firefly luciferase enzyme. It has a red-shifted bioluminescence emission maximum at 600 nm and is suitable for bioluminescence imaging studies in living subjects.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Selênio / Luciferina de Vaga-Lumes Limite: Animals / Humans Idioma: En Ano de publicação: 2012 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Selênio / Luciferina de Vaga-Lumes Limite: Animals / Humans Idioma: En Ano de publicação: 2012 Tipo de documento: Article