[Chemical studies on alkaloids of Chinese medicinal herbs Daphniphyllum macropodum].
Zhongguo Zhong Yao Za Zhi
; 36(22): 3134-6, 2011 Nov.
Article
em Zh
| MEDLINE
| ID: mdl-22375393
ABSTRACT
OBJECTIVE:
To study the alkaloids of the Chinese medicinal herbs Daphniphyllum macropodum for in search for new bioactive substances.METHOD:
The CHCl3 extract of D. macropodum was subjected to repeated column chromatography on silica gel to afford four pure compounds (1-4). Their structures were determined on the basis of detailed spectroscopic analysis and comparison with the data reported in the literature.RESULT:
The four known compounds were isolated and elucidated as Daphniphyllum alkaloids with different carbon skeletons, namely longistylumphylline A (1), deoxycalyciphylline B (2), daphnicyclidin B (3) and H (4), respectively.CONCLUSION:
All compounds were isolated from the titled plant for the first time. The discovery of daphnicyclidin B (3) and H (4) further confirmed the biogenetic relationship between the two compounds and the previously reported macropodumines A-C, found in the same plant.
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Base de dados:
MEDLINE
Assunto principal:
Medicamentos de Ervas Chinesas
/
Magnoliopsida
/
Alcaloides
Idioma:
Zh
Ano de publicação:
2011
Tipo de documento:
Article