A lamotrigine induced toxic epidermal necrolysis in a child.
Cutan Ocul Toxicol
; 32(1): 86-8, 2013 Mar.
Article
em En
| MEDLINE
| ID: mdl-22380023
ABSTRACT
Toxic epidermal necrolysis (TEN) is rare, life-threatening skin disorder that usually is caused by an adverse drug reaction. The exact pathogenesis of TEN is still unknown. Many treatments including prednisolone, cyclosporine and intravenous immunoglobulin (IVIG) can be used to halt the disease process. We present a 12-year-old girl with epilepsy who developed TEN after about 14 days of lamotrigine treatment. Lamotrigine was immediately discontinued. After receiving systemic corticosteroid treatment, the patient had a complete recovery. Antiepileptic-induced TEN can be mortal in some cases. Thus, we would like to point out the importance of early diagnosis and treatment.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Triazinas
/
Síndrome de Stevens-Johnson
/
Anticonvulsivantes
Tipo de estudo:
Screening_studies
Limite:
Child
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article