Flow-independent 3D whole-heart vessel wall imaging using an interleaved T2-preparation acquisition.
Magn Reson Med
; 69(1): 150-7, 2013 Jan.
Article
em En
| MEDLINE
| ID: mdl-22392553
ABSTRACT
Current techniques to visualize the arterial vessel wall are limited in coverage because most of them are flow dependent. In this study, we present a novel technique for flow-independent vessel wall imaging that takes advantage of the differences in T2 relaxation time of arterial blood and surrounding tissues using the T2-preparation prepulse. The technique is based on the acquisition and subtraction of two data sets, one obtained with and one without T2-preparation prepulse. This approach allows for nulling the signal of arterial blood while maintaining signal from muscle and vessel wall. The result of the subtraction is a flow-independent black-blood vessel wall image. To minimize the motion sensitivity of the subtraction step, we developed an interleaved acquisition for the T2-preparation prepulse and non-T2-preparation prepulse images, which allows obtaining coronary vessel wall images from a whole-heart acquisition with minimal misregistration artefacts. In this article, we present the technique and preliminary results in healthy subjects.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Aorta Torácica
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Angiografia por Ressonância Magnética
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Vasos Coronários
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article