A standard blood bank donation alters the thermal and cardiovascular responses during subsequent exercise.
Transfusion
; 52(11): 2339-47, 2012 Nov.
Article
em En
| MEDLINE
| ID: mdl-22452709
ABSTRACT
BACKGROUND:
The fear for adverse effects of blood donation on subsequent exercise may prevent physically active people from donating. We studied the impact of a standard blood bank donation (i.e., 450-mL blood withdrawal) on the thermoregulatory and cardiovascular responses to prolonged exercise in the heat. STUDY DESIGN ANDMETHODS:
Eight moderately trained, heat-acclimated males cycled for 1 hour at 60% in a hot environment (34.9±0.6 °C) on four occasions 1) 2 days before blood donation (CON), 2) 2 hours after donation (DON), 3) 2 days after donation (2 DAYS), and 4) 7 days after donation (7 DAYS).RESULTS:
Two-thirds of the blood volume withdrawn was endogenously restored before exercise in the DON trial (p<0.05). DON started with increased preexercise rectal temperature (TRE; 0.42±0.1 °C above CON; p<0.05), which resulted in high levels of hyperthermia (i.e., 39.0±0.2 °C) after 1 hour of exercise. Skin temperature (34.5±0.1 °C) and sweat rate (1.15±0.1 L/h) were not affected by DON. However, DON lowered the skin blood flowTRE relationship and elevated heart rate (HR) above CON (12±4 beats/min; p<0.05) maintaining cardiac output. After 2 DAYS, TRE and HR were restored to CON levels while cardiac output increased above CON (6%; p<0.05) in association with reduced hemoglobin concentration (i.e., peak hemodilution).CONCLUSION:
A blood bank donation increases preexercise TRE. Subsequent exercise in a hot environment results in high levels of hyperthermia and HR. These thermoregulatory and cardiovascular perturbations observed during exercise disappear 2 days after donation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doadores de Sangue
/
Regulação da Temperatura Corporal
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Exercício Físico
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Febre
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Aclimatação
Limite:
Adult
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Humans
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Male
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article