Experimental murine model of disseminated infection by Saksenaea vasiformis: successful treatment with posaconazole.
Med Mycol
; 50(7): 710-5, 2012 Oct.
Article
em En
| MEDLINE
| ID: mdl-22458251
ABSTRACT
We have determined the in vitro activity of amphotericin B (AMB) and posaconazole (PSC) against Saksenaea vasiformis using broth microdilution and disk diffusion methods and determined the minimal fungicidal concentration (MFC). PSC was found to have the greatest in vitro activity in all cases and was the most efficacious in prolonging survival and reducing the fungal load in an immunocompetent murine model of disseminated infection caused by four strains of the fungus.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Triazóis
/
Modelos Animais de Doenças
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Mucorales
/
Mucormicose
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Antifúngicos
Limite:
Animals
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article