[Study on in vitro susceptibility of Candida spp. isolated from blood culture]. / Studio sulla incidenza e sulla sensibilità in vitro di ceppi di Candida spp. isolati da sangue.

ABSTRACT

In recent years the incidence of bloodstream infections due to Candida species has progressively increased, partly due to the more critical conditions of hospitalized patients. There has been a significant increase in immune-compromised, diabetic and/or elderly patients, also with venous access, with a subsequent increase in Candida species isolated from bloodstream infections. In 2009-2010 in the hospitals of Mestre and Venice we isolated 123 Candida species from bloodstream infections 59 Candida albicans, 28 Candida parapsilosis, 12 Candida glabrata, 9 Candida tropicalis, and 4 Geotrichum capitatum, while the 11 others belong to 8 different species. We calculated MIC for the following antifungal agents fluconazole, itraconazole, voriconazole, 5-flucytosine, amphotericin B and caspofungin.