Mechanical stress acts via katanin to amplify differences in growth rate between adjacent cells in Arabidopsis.
Cell
; 149(2): 439-51, 2012 Apr 13.
Article
em En
| MEDLINE
| ID: mdl-22500806
ABSTRACT
The presence of diffuse morphogen gradients in tissues supports a view in which growth is locally homogenous. Here we challenge this view we used a high-resolution quantitative approach to reveal significant growth variability among neighboring cells in the shoot apical meristem, the plant stem cell niche. This variability was strongly decreased in a mutant impaired in the microtubule-severing protein katanin. Major shape defects in the mutant could be related to a local decrease in growth heterogeneity. We show that katanin is required for the cell's competence to respond to the mechanical forces generated by growth. This provides the basis for a model in which microtubule dynamics allow the cell to respond efficiently to mechanical forces. This in turn can amplify local growth-rate gradients, yielding more heterogeneous growth and supporting morphogenesis.
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Base de dados:
MEDLINE
Assunto principal:
Arabidopsis
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Adenosina Trifosfatases
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Meristema
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Proteínas de Arabidopsis
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article