Utility of apparent diffusion coefficient ratios in distinguishing common pediatric cerebellar tumors.
Acad Radiol
; 19(7): 794-800, 2012 Jul.
Article
em En
| MEDLINE
| ID: mdl-22513110
ABSTRACT
RATIONALE AND OBJECTIVES:
The aim of this study was to identify clinically useful tumor/normal brain apparent diffusion coefficient (ADC) ratios for distinguishing common pediatric cerebellar tumors. MATERIALS ANDMETHODS:
Review of medical records revealed 79 patients with cerebellar tumors who underwent preoperative magnetic resonance imaging, including diffusion-weighted imaging sequences, and surgery. There were 31 pilocytic astrocytomas, 27 medulloblastomas, 14 ependymomas, and seven atypical teratoid/rhabdoid tumors. ADC values were measured by placing regions of interest on the solid tumor and normal brain parenchyma by two reviewers. Tumor/normal brain ADC ratios were calculated.RESULTS:
Mean ADC values of the pilocytic astrocytomas were greater than those of ependymomas, whose mean ADC values were greater than those of medulloblastomas and atypical teratoid/rhabdoid tumors. Using a tumor/normal brain ADC ratio threshold of 1.70 to distinguish pilocytic astrocytomas from ependymomas, sensitivity of 92% and specificity of 79% were achieved. A tumor/normal brain ADC ratio threshold of 1.20 enabled the sorting of ependymomas from medulloblastomas with sensitivity of 93% and specificity of 88%.CONCLUSIONS:
Tumor/normal brain ADC ratios allow the distinguishing of common pediatric cerebellar tumors.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Astrocitoma
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Neoplasias Cerebelares
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Tumor Rabdoide
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Imagem de Difusão por Ressonância Magnética
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Ependimoma
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Meduloblastoma
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article