[Cardiovascular pharmacology. An example of the need of clinically relevant pharmacological research]. / Herz- und Kreislaufpharmakologie. Ein Beispiel der Notwendigkeit kliniknaher pharmakologischer Forschung.
Wien Klin Wochenschr
; 102(20): 593-601, 1990 Oct 26.
Article
em De
| MEDLINE
| ID: mdl-2256341
ABSTRACT
Like all other scientific disciplines, preclinical pharmacological research is subject to permanent changes. New measuring devices and the possibility of continuous on line data acquisition have markedly influenced basic research in this field. Another aim of modern cardiovascular pharmacology is the testing of promising drugs in clinically relevant animal models of disease, particularly under conditions, referring to the everyday situation in patients, e.g. physical activity. Investigations carried out in this way allow an exact assessment of the clinical efficacy of new drugs, and are, thus, clearly indispensable, also from the ethical point of view, before primary evaluation of the drug in man.
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Base de dados:
MEDLINE
Assunto principal:
Farmacologia
/
Fármacos Cardiovasculares
Limite:
Animals
/
Humans
País como assunto:
Europa
Idioma:
De
Ano de publicação:
1990
Tipo de documento:
Article